• Romiplostim is an Fc fusion protein that augments thrombopoi

  2019-04-15

  

  Romiplostim is an Fc-fusion protein that augments thrombopoiesis by binding to and activating the thrombopoietin receptor. It is approved for the treatment of thrombocytopenia in patients with chronic immune thrombocytopenic purpura who have had an insufficient response to corticosteroids, immunoglo

• Predicting the potential effects of climate change on

  2019-04-15

  

  Predicting the potential effects of climate change on the incidence and distribution of infectious gastroenteritis can assist public health providers to control and prevent severe outbreaks in the future. Implementation of programmes for rotavirus vaccination clearly shows benefit and should be an a

• Acute kidney injury is a common disorder worldwide

  2019-04-15

  

  Acute kidney injury is a common disorder worldwide, occurring in more than 13 million people every year, 85% of whom live in low-income or middle-income countries (LMICs). The disease imposes a severe burden of morbidity and mortality, with a major economic effect on health-care expenditure worldwid

• prosecute The distribution of dental treatments and the numb

  2019-04-15

  

  The distribution of dental treatments and the number of treated teeth within each age group were also analyzed. The  6-years-old group had the lowest mean number of teeth treated by stainless-steel crown (SSC) and the lowest number undergoing pulp therapy (pprosecute and, when compared against 2015

• Numbers studies also showed that the MSCs have

  2019-04-15

  

  Numbers studies also showed that the MSCs have the capacity to differentiate into multiple mesenchymal tissues both in vitro and in vivo, including osteoblast [25,34], condrocyte [35,36], adipocyte [37,38], tendon [39,40], skeletal muscle cells [39], cardiomyocyte [41,42] and hematopoietic supportin

• br Conflict of interest br Acknowledgments

  2019-04-15

  

  Conflict of interest Acknowledgments Introduction Compared to the traditional right atrial appendage (RAA) pacing, inferior interatrial septum (IAS) pacing around the coronary sinus ostium significantly reduces paroxysmal atrial fibrillation (AF) burden and recurrence and slows the progress

• br Conflict of interest br

  2019-04-15

  

  Conflict of interest Introduction Case report A 5-year-old boy was admitted for treatment of atrial flutter after correction of pulmonary atresia with ventricular septal defect. The patient had undergone total correction of cardiac disease at 4 years and 2 months of age after previous bilat

• GP ablation has been regarded as a vagal denervation procedu

  2019-04-15

  

  GP ablation has been regarded as a vagal denervation procedure that reduces the vagal tone in the atria and the vulnerability to AF. However, it is unclear how much vagal effect on the atrium is attenuated and how much of the atrium is denervated after the ablation. According to the GP mapping by Mc

• Stroke is second only to ischaemic heart disease as the

  2019-04-15

  

  Stroke is second only to ischaemic gap-26 disease as the leading cause of death worldwide; one in six people will have a stroke in their lifetime. , on October 29, reminds us of these striking facts and the need for individuals to know the risk factors. Although the main risk factors for stroke worl

• La imagen de la Virgen de

  2019-04-15

  

  La imagen de la Virgen de Caacupé junto con sus celebraciones religiosas y su devoción llegó a la ciudad en 1993 en forma de obsequio de una compatriota paraguaya a la agrupación arpa. A partir de entonces, la colectividad incorporó la práctica religiosa devocional no sólo como uno de los actos más

• In an earlier study we used a questionnaire to

  2019-04-15

  

  In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In t

• br Conflict of interest br

  2019-04-15

  

  Conflict of interest Introduction A large number of recent reports suggest that early repolarization (ER) and J waves are associated with the occurrence of ventricular fibrillation (VF) [1–4]. In particular, the presence of J waves in global leads, including the inferolateral leads, is thought

• br Case report A year old female presented

  2019-04-15

  

  Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (HMBA Linker manufacturer of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubi

• br D microCT data Bone volume BV TV

  2019-04-15

  

  3D microCT data Bone volume (BV/TV) ranged from 10.8 to 13.5% consistent with the published literature [18]. Trabecular thickness (Tb.Th), trabecular cysteine protease (Tb.Sp), trabecular number (Tb.N) and bone surface per tissue area (BS/TV) values were also consistent with the range published i

• br Discussion The presence of metastases at the

  2019-04-11

  

  Discussion The presence of metastases at the time of diagnosis is a significant prognostic factor in osteosarcoma [14]. Skeletal metastases at time of presentations appears to carry a worse prognosis than pulmonary metastases [15]. Furthermore, the chance of survival can be improved by surgical r

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