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A recent analysis recommended axillary
2019-04-26
A recent analysis recommended axillary staging by sentinel lymph node biopsy, and administration of adjuvant radiotherapy and endocrine therapy after breast conserving surgery for mucinous carcinoma. Park et al. concluded that adjuvant chemotherapy could potentially be omitted in cases with favorab
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The effects of zoledronic acid are most
2019-04-26
The effects of zoledronic SCH527123 are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Where
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br Methods br Results br
2019-04-26
Methods Results Discussion One of the hallmarks of cancer is the ability of cancer ampk pathway to evade apoptosis. Inhibition of apoptosis not only enhances the survival of cancer cells but also facilitates their escape from chemotherapy [5]. Therefore, apoptosis regulatory mechanisms are
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Rate dependent RBBB is not commonly observed during routine
2019-04-26
Rate-dependent RBBB is not commonly observed during routine clinical exercise testing [8]. In the S-ICD, when new RBBB arises, the QRS-T wave morphology recorded by the device may also change. In this case, the R/T wave ratio may decrease to a threshold where the T wave is above the sensing decay cu
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A structured inherited arrhythmia or heart
2019-04-26
A structured inherited arrhythmia (or heart disease) clinic provides the platform for optimized multidisciplinary evaluation and management of patients and families with suspected inherited heart disease. The collective efforts of the core staff and access to a variety of experts in related discipli
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Involvement of the ventricular myocardium
2019-04-26
Involvement of the ventricular myocardium can lead to delayed conduction or anatomical obstacles that are labile to ventricular tachyarrhythmia. Arrhythmias are independently predictive of sudden cardiac death (SCD) [9]. SCD is common in patients with cardiac AL amyloidosis, and prophylactic implan
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Si en La virgen de los sicarios la vida crapulosa
2019-04-25
Si en La virgen de los sicarios “la vida crapulosa está derrotando igf1r la muerte”, y “anda toda ventiada por Medellín día y noche en su afán haciendo lo que puede, compitiendo con semejante paridera, la más atroz [y] este continuo nacer de niños y el suero oral le están sacando canas”, para Ramíre
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BTL-104 C mo ha reaccionado la literatura m s
2019-04-25
¿Cómo ha reaccionado la literatura más reciente de América Latina ante estas realidades? Esta pregunta o, más bien, las posibles respuestas BTL-104 ésta, le confieren su estructura reflexiva y argumental al libro, que no tiene, y esto es agradecible y estimulante, una pretensión canónica, sino que a
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First progress towards the targets
2019-04-25
First, progress towards the 2020 targets should be measured through collation, presentation, and analysis of standardised core metrics that track country progress. Elimination and control targets in the WHO Roadmap could serve as initial standardised metrics. Efforts are being made to measure the pr
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We did a qualitative analysis to estimate
2019-04-25
We did a qualitative analysis to estimate the potential risk of Zika PD 0332991 cost introduction into the country. We used the circlize statistical package for R software to visualise incoming traffic (logarithm of relative passenger volume) to Pakistani airports from countries characterised as Zik
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In high income settings the prevalence of tobacco
2019-04-25
In high-income settings, the prevalence of tobacco use has been shown to be significantly higher in people living with HIV than among HIV-negative individuals of the same age and sex distribution. This at-risk pattern is one of the biggest threats to the number of years of life saved with antiretrov
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It is generally believed that the pelvis is
2019-04-25
It is generally believed that the pelvis is possibly the most accurate bone in the human body for gender determination, with the accuracy being 95% when completed. In addition, it is estimated that the accuracy of gender identification from the subpubic angle, ventral arc, and composite is approxima
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The diagnosis is very difficult on radiographical imaging al
2019-04-25
The diagnosis is very difficult on radiographical imaging alone as many tumours have similar radiological appearances to desmoplastic fibroma [2,7]. Biopsy is the gold standard method of determining the exact nature of any bony lesion as it provides a tissue diagnosis. The biopsy ideally should be p
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Algunos cambios sin embargo estaban llegando para tener gran
2019-04-25
Algunos cambios, sin embargo, estaban llegando para tener gran influencia. En la Europa nórdica ciertos oscuros eruditos habían empezado NCT-501 crear las bases de una ciencia fundamental para la burguesía moderna, la filología clásica, y sobre ella un neohumanismo fundamentado en la resurrección de
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Hydrogen peroxide H O is shown to readily
2019-04-24
Hydrogen peroxide (H2O2) is shown to readily promote EADs and triggered activity in isolated rat and rabbit ventricular myocytes by increasing both the L-type Ca channel (ICa-L) and late sodium currents (INa-L) [31–35]. However, this same stress fails to cause EADs in normal non-fibrotic cardiac tis
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