• br A tactical change in research and advocacy is

  2019-05-13

  

  A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di

• More than million almost children

  2019-05-13

  

  More than 200 million—almost 40%—children younger than 5 years in developing countries are not fulfilling their developmental potential. In parts of Africa, up to three-quarters of children are victims of physical abuse, and a third of girls and more than 10% of boys are victims of sexual abuse. One

• Seg n Buitrago en Centroam rica prevaleci

  2019-05-13

  

  Según Buitrago, en Centroamérica prevaleció o fue determinante el último componente de la dsn proveniente de Estados Unidos. Es muy factible que quienes afirman que “la adopción y adaptación de la dsn en Guatemala anticiparon las de otros países de América Latina” aludan ras pathway esa omnipresenci

• Of note gender equity might continue despite the

  2019-05-13

  

  Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low

• br Introduction Incidence of oral

  2019-05-13

  

  Introduction Incidence of oral cancers accounts for ∼3% of all malignancies. Oral squamous cell carcinoma (OSCC) accounts for >95% of all malignancies in the oral cavity, and it is the fifth leading cause of cancer death in the male population in Taiwan. OSCC is treated mainly with surgery. Post

• IL can induce phagocytosis cytoskeleton rearrangement gene

  2019-05-13

  

  IL-15 can induce phagocytosis, cytoskeleton rearrangement, gene expression, de novo protein synthesis and can delay apoptosis in human neutrophils [15]. Production of chemokines, cytokines and natural inhibitors is increased in IL-15 induced neutrophils, including CXCL8 (IL-8) [16], IL-1beta, IL-1RI

• Introduction Atrial fibrillation AF is a highly prevalent at

  2019-05-13

  

  Introduction Atrial fibrillation (AF) is a highly prevalent atrial arrhythmia that affects approximately 10% of individuals older than 75 years of age and tends to increase in prevalence with advancing age [1–3]. Although AF itself is not life threatening, it is a risk factor for stroke, and the AF

• br ECM cancer and metastasis For cells

  2019-05-10

  

  ECM, cancer and metastasis For THZ1 to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-documented hallmark of cancer.

• br Conclusion br Funding br Conflict of interest

  2019-05-10

  

  Conclusion Funding Conflict of interest Introduction Over the last decade, the unabated increase in the number of transseptal catheterizations has been related to an increase in atrial fibrillation (AF) ablation procedures. Transseptal puncture (TP) is usually safe in experienced hands [

• Because our patient s native rhythm remained AV block

  2019-05-10

  

  Because our patient׳s native rhythm remained 2:1 AV block with a narrow QRS, we attempted HBP as the first-line treatment based on the assumption that His-Purkinje conduction might be preserved. Another benefit of HBP in this patient with CKD is that the use of iodinated focal adhesion kinase inhibi

• De manera concomitante la confecci n

  2019-05-10

  

  De manera concomitante, la confección de relaciones y crónicas devino una forma de obtener recompensas o beneficios del favor real. De este modo, tanto particulares como miembros de corporaciones (v. gr. la iglesia) elaboraron sus historias (manuscritas o impresas) y buscaron hacerlas llegar al mona

• El Grounded Theory permite un an lisis

  2019-05-10

  

  El Grounded Theory permite un análisis mucho más profundo y cualitativo de estos textos constitucionales. Si además los concebimos como “narrativas constitucionales”, escritas por muchas manos (los participantes directos o indirectos de las Asambleas Constituyentes) con la pretensión de definir el s

• Treatment options for elderly AML must be based on four

  2019-05-10

  

  Treatment options for elderly AML must be based on four main factors: patient\'s clinical condition, disease characteristics, patient wishes and social support. Thus, the most frail and oldest among the oldest will have the least net benefit from chemotherapy or hematopoietic transplantation, even i

• br Purpose br Methods Participating centers

  2019-05-10

  

  Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register

• br CaMKII and heart failure progression CaMKII

  2019-05-10

  

  CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com

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