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sphingosine kinase br ECM cancer and metastasis For cells
2019-05-06
ECM, cancer and metastasis For sphingosine kinase to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-documented hallm
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br Therapy for the CPVT br Conflict of
2019-05-06
Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele
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Introduction Myelodysplastic Syndrome MDS is a heterogeneous
2019-05-05
Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal
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ZIKV is a flavivirus related to
2019-05-05
ZIKV is a flavivirus related to dengue virus (DENV) and historically has been transmitted by the same mosquito species, (). There is no available treatment or vaccine so disease control is limited to the management of mosquitoes which currently relies on either insecticides or the destruction of la
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It s April and the
2019-05-05
It\'s (April 25) and the theme is “End malaria for good”. If I\'m not mistaken, that means eradication. In one of the first Comment pieces ever published, asked “Is it possible? Is it worth it? Should we do it?” and the methane monooxygenase is still divided. Despite remarkable progress in pr
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Early repolarization ER is characterized by elevation of the
2019-05-05
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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In Telek Ayove and colleagues report a comparison
2019-05-05
In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi
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br Discussion CRT has become
2019-05-04
Discussion CRT has become an established adjunctive treatment to optimal pharmacological therapy in patients with advanced CHF, diminished LV function, and intra-ventricular conduction delay [8]. Despite the benefits of CRT including improvements in exercise capacity, functional class, and ventri
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IRF expression had previously been described as a factor
2019-05-04
IRF1 expression had previously been described as a factor that contributes to susceptibility for HIV-1 infection [14]. Our findings evidenced a different expression modulation of this transcription factor in the two groups of DC according with the expression of the important Th1 driving cytokine IL-
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After CRT D implantation the QRS
2019-05-04
After CRT-D implantation, the QRS duration decreased to 122ms (Fig. 2), and the cardiac dyssynchrony improved. However, 5 days after implantation, atrial flutter (AFL) and electrical storm presenting as frequent VT were seen. As shown in Fig. 3A, the VT was initiated by a premature ventricular compl
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Roux en Y gastric bypass surgery is a
2019-05-04
Roux-en-Y gastric bypass surgery is a common cause of malabsorption associated with hyperoxaluria in obese patients and those with malignancies. Postoperatively, patients may have steatorrhea, weight loss, and diarrhea, resulting in malabsorption syndrome, which would increase excessive intraluminal
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br Materials and methods br Results br Discussion br Conclus
2019-05-04
Materials and methods Results Discussion Conclusions Immediate ablation discontinuation during pulmonary vein isolation remarkably decreased the incidence of EsoTLs, even when using STS. EsoTL did occur after AFRA with immediate ablation discontinuation at the esophageal temperature prob
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br Las medidas que toma
2019-05-04
Las medidas que toma el gobierno argentino y que abordamos en este apartado no se comprenden disociadas de este clima transnacional que marca un rumbo y delinea objetivos comunes para definir y afrontar la cuestión social. Ya en 2003, adopta un posicionamiento público respecto 2-deoxy-d-glucose la
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br Authorship br Conflict of interest
2019-05-04
Authorship Conflict of interest disclosure Introduction The Aurora kinases are serine/threonine protein kinases essential for regulation of normal meclizine hcl mitosis. Aurora kinases A (AAK) and B are overexpressed in hematologic malignancies, including acute myeloid leukemia (AML) and m
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It is generally believed that the pelvis is
2019-05-04
It is generally believed that the pelvis is possibly the most accurate bone in the human body for gender determination, with the accuracy being 95% when completed. In addition, it is estimated that the accuracy of gender identification from the subpubic angle, ventral arc, and composite is approxima
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