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3-Chlorotyrosine br Introduction Diamond nucleic scid dye
2020-07-31
Introduction Diamond™ nucleic scid dye (DD) (Promega, Madison, WI, USA) has recently been reported to stain DNA in samples such as hair roots and shafts [1], [2], saliva [3], [4], fingermarks [5] and other forensically relevant items [6]. The DD molecule is an external groove-binder that is able
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br Conclusion br Conflict of interest br Introduction The se
2020-07-31
Conclusion Conflict of interest Introduction The sexual exploitation and internal trafficking of British children within the UK has received growing public and policy attention in recent years. This has largely been in response to a number of high profile police investigations into cases in
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Expression of MGMT in human cells can be switched
2020-07-31
Expression of MGMT in human H-Lys(Z)-OH can be switched off by enzymatic methylation of a cytosine residue in the MGMT promoter sequence. In this regard, both MGMT and the mismatch repair function MLH1 belong to a subset of DNA repair genes that are subjected to epigenetic control. In consequence, a
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Some V PPase genes of plants are inducible and
2020-07-30
Some V-PPase genes of plants are inducible and have essential roles in plant development and response to environmental changes [4], [36]. Stress conditions, such as cold, anoxia, chemical stimulation, wound, salt, osmotic shock and plant hormones, etc., could induce the gene 2797 and enhance the act
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br Hypothesis on DDR protective mode of
2020-07-30
Hypothesis on DDR1 protective mode of action The documented protective role of DDR1 is quite impressive, demonstrated using different preclinical models (immunologic [46,54,58], obstructive [45], and hypertensive [50]) with different intervention paradigms: genetic ablation [45,50,58,72], silenci
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Flow cytometric analyses indicated that CysLT receptor posit
2020-07-30
Flow cytometric analyses indicated that CysLT2 receptor-positive leukocytes included Siglec F+ Octreotide acetate (eosinophils), CD11c+ F4/80+ cells (alveolar macrophages), and CD11c+ I-A/I-E+ cells (conventional dendritic cells). Only a small percentage of Gr-1+ cells (neutrophils) was positive fo
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In the present study it was found that
2020-07-30
In the present study, it was found that HepG2, H4IIE and LMH cells were inclined to remove S-metalaxyl and lead to decrease of ERs of metalaxyl, while L8824 cells were inclined to attenuate R-metalaxyl and resulted in an inverse shift of ER. These findings indicate the enantioselective accumulation
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Owing to the variation of inactive protein kinase
2020-07-30
Owing to the variation of inactive protein kinase conformations as compared with the conserved active conformation, it was suggested that type II inhibitors would be more selective than type I inhibitors, which bind to the canonical active conformation. The results of Vijayan et al. support this sug
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br Introduction Epstein Barr virus induced G protein coupled
2020-07-29
Introduction Epstein-Barr virus-induced G protein-coupled receptor 2 (EBI2, also known as GPR183) was discovered in 1993 in a screen of genes induced by in vitro Epstein-Barr virus (EBV) infection of a Burkitt’s lymphoma cell line (Birkenbach et al., 1993) and identified by sequence similarity as
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Similarly research ranking RESEARCH was not significant in t
2020-07-29
Similarly, research ranking (RESEARCH) was not significant in the model so H7 is not supported. Contrary to the findings of Bline et al., 2016b, Boone et al., 2006, the current study did not find an association between faculty research productivity and exam pass rate. This could be due to difference
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br Materials and methods br Discussion To date only
2020-07-28
Materials and methods Discussion To date, only a fraction of studies pertaining to analysis of avian semen have focused on the study of DNA, with the vast majority being associated with the effects of cryopreservation on sperm DNA integrity (Kotłowska et al., 2007, Madeddu et al., 2009, Partyk
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Natural product lapachol was isolated by basic acid
2020-07-28
Natural product lapachol (1) was isolated by basic/acid work up and further purified by silica column chromatography and the synthesized compounds were evaluated for their in vitro antimalarial activity against P. falciparum W2 that is a chloroquine resistant and mefloquine-sensitive strain. Table 1
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Calmodulin CaM is a multifunctional
2020-07-28
Calmodulin (CaM) is a multifunctional calcium transducer [8]. It functions as a central regulator of cellular metabolism in response to changes in cellular calcium levels by interacting with various targets [9]. Numerous studies have been devoted to the understanding CaM mechanism of action. Early m
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In the cytoplasm the ternary CRM cargo
2020-07-28
In the cytoplasm, the ternary CRM1–cargo–RanGTP complex is disassembled by the action of Ran-binding proteins RanBP1/2 and RanGAP. A recent kinetic study showed that the Ran-binding domains (RanBDs) of the cytoplasmic proteins RanBP1 and RanBP2, but not RanGAP, accelerate dissociation of NES from CR
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Sex also influences COMT effects on cognition
2020-07-28
Sex also influences COMT effects on cognition. Women have 20%–30% less COMT activity than men (Chen et al., 2004, Fahndrich et al., 1980). Both Raz et al. (2011)O\'Hara et al. (2006) found that sex interacted with COMT genotype such that older men who had a Val allele showed greater negative effects
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