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One of the most common dietary approaches against obesity as
2021-09-16

One of the most common dietary approaches against obesity-associated diseases is the increase in the consumption of ω3 polyunsaturated fatty acids [18], [19]. Since seminal paper by Bang and Dyeberg in which the low prevalence of coronary heart disease among the Inuit was associated with the high ma
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Several studies have found that GPR possesses a distinct
2021-09-16

Several studies have found that GPR55 possesses a distinct pharmacology from that of CB1 and CB2, and that only certain cannabinoids act at this receptor. In transfected Benzethonium Chloride expressing hGPR55, out of more than 20 synthetic and endogenous cannabinoids evaluated, only 2 compounds, S
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Overall our results indicated the involvement of GABAAR in
2021-09-16

Overall, our results indicated the involvement of GABAAR in controlling GnRH/LH release through mechanism which included GABA action on molecular processes leading to GnRH biosynthesis. This is consistent with previous in vivo [14,54] and in vitro [55] studies in ewes suggesting that GABA inhibits G
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Oxidative stress results from the disequilibrium
2021-09-16

Oxidative stress results from the disequilibrium between levels of prooxidant molecules produced and the ability of a biological system to detoxify and neutralize the reactive molecules [14]. OS is a chronic, self-perpetuating state of damage to cells and increased inflammation resulting from the co
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br Materials and methods br Results and
2021-09-16

Materials and methods Results and discussion Conclusions In summary, the Au@SiO2 based lateral flow sandwich immunoassay for fast detection of EBN-specific glycoprotein has been firstly established by using nanocomposites as signaling-labels and synthesized EBN-specific mst2 as recognition
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Depending upon the varied habitats e g
2021-09-16

Depending upon the varied habitats (e.g. soil, water, animal digestive tracts, etc.), microbes possess a diverse range of carbohydrate ABC transporters and metabolic pathways (Rodionov et al., 2013; Bräsen et al., 2014). Thermus thermophilus HB8, a thermophilic gram-negative bacterium dwelling in ho
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br Conclusion These are exciting times in EAAT research
2021-09-16

Conclusion These are exciting times in EAAT research. The discovery and use of the GltPh and GltTk transporters as model systems for EAATs has provided detailed understanding of structure–function aspects of the transporters. Moreover, recent studies into the physiological functions of the transp
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To evaluate SLC A abundance after transfection
2021-09-16

To evaluate SLC45A1 abundance after transfection, we performed western blots. Transfected COS-7 BKT140 were lysed and separated for membrane fraction. Equal amounts of proteins from membrane fractions were resolved by SDS-PAGE, transferred to a nitrocellulose filter, and immunoblotted with an anti-S
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FPR activation stimulates multiple signal transduction pathw
2021-09-15

FPR1 activation stimulates multiple signal transduction pathways responsible for various neutrophil functions, such as adhesion, chemotaxis, phagocytosis, 366 2 of secretory granules, and superoxide anion radical (O2) production, which contribute to the physiological inflammatory response associate
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Cap Firefly Luciferase mRNA Moving forward to series the ene
2021-09-15

Moving forward to series , the energy minimized conformation of Cap Firefly Luciferase mRNA within the binding pocket is quite interesting. The indole-based tail guides the TZD head for a highly-favored interaction with all residues of the H-bonding triad (). In addition, an extra bonding with H44
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apexbio calculator FBPase deficiency is a very rare inborn
2021-09-15

FBPase deficiency is a very rare inborn error of fructose apexbio calculator of autosomal recessive inheritance. This disorder usually occurs in the first year of life through ketotic hypoglycemia and lactic acidosis triggered by catabolic episodes such as prolonged fasting or febrile infections (S
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br FAAH regulation of ECB signaling ECBs
2021-09-15

FAAH regulation of ECB signaling ECBs are fatty JSH-23 amides and monoacylglyerols functioning as neuromodulator lipids that exhibit rapid (within seconds) on-demand biosynthesis in response to neuronal activation, and are subsequently degraded by specialized catabolic enzymes. There are two kno
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br Discussion In our study the prevalence of severe periodon
2021-09-15

Discussion In our study the prevalence of severe periodontitis in patients with HIV infection was 66%, almost twice as high as in uninfected controls. Our results are in line with the prevalence of severe periodontitis found in HIV-infected patients in London, United Kingdom in the pre-cART era:
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br Results br Discussion The
2021-09-15

Results Discussion The present findings outline a novel regulatory mechanism for fasting-induced ketogenesis, which involves histamine release from mast hydroxychloroquine sulfate into the hepatic portal system, H1 receptor-mediated stimulation of liver OEA biosynthesis, and recruitment of th
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Obesity is one of the worldwide
2021-09-15

Obesity is one of the worldwide concerns, with high prevalence and adverse effects on human health and life expectancy. According to the World Health Organization (WHO), obesity is defined as abnormal or excessive fat accumulation in the body with body mass index (BMI) of 30 or more. Obesity increas
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