• br Theory and hypotheses br Methodology

  2018-11-15

  

  Theory and hypotheses Methodology Data analysis Table 1 provides means, standard deviations and bivariate correlations of all the variables. The correlations coefficients provide initial support for our study hypotheses. Consistent with our hypotheses, the bivariate correlations indicate th

• JNK signaling promotes the expression

  2018-11-14

  

  JNK signaling promotes the expression of cytoprotective genes in flies, which contributes to tissue homeostasis loss in aged guts (Biteau et al., 2008). We found that JNK activity was increased in dbr- and ptc-depleted guts, and further inhibition of JNK activity in these guts effectively suppressed

• leukotriene receptor antagonists Chromatin at mammalian telo

  2018-11-14

  

  Chromatin at mammalian telomeres is underacetylated and shares the typical features of other repeat-containing constitutive heterochromatic elements, such as pericentric chromatin. Telomeric repeats are also enriched for H3K9me3, which represents a docking site for the binding of HP1 isoforms (Benet

• Although MaSCs i e bipotent basal stem cells

  2018-11-14

  

  Although MaSCs (i.e., bipotent basal stem cells) were initially hypothesized as carboxypeptidase a of origin of breast cancer, recent studies suggested that most breast cancers, including basal-like breast cancer (BLBC), might originate from luminal cells (Skibinski and Kuperwasser, 2015). In parti

• br Discussion In this study we demonstrate that

  2018-11-14

  

  Discussion In this study, we demonstrate that more than a quarter of AF patients have CKD, and that age, female sex, CHF, previous stroke/TIA and the occurrence of paroxysmal AF were significantly associated with CKD in AF patients. Second, we found a linear association between CrCl and TTR in AF

• br Introduction Core binding factor CBF is a heterodimeric

  2018-11-14

  

  Introduction Core binding factor (CBF) is a heterodimeric transcription factor composed of a DNA-binding RUNX subunit (encoded by one of three genes: RUNX1, RUNX2, or RUNX3) and a non-DNA-binding CBFβ subunit which increases the affinity of RUNX proteins for DNA. All three RUNX proteins as well a

• br Funding Source This study was funded

  2018-11-14

  

  Funding Source This study was funded by Mesoblast, Inc. Contributors Declaration of Interests Prior Presentation Acknowledgements Introduction In 1933, Henrik Sjögren, in his doctoral dissertation introduced the neologism, keratoconjunctivitis Sicca (Murube, 2010, Sjögren, 1933).

• According to HCV status we found a stronger association

  2018-11-14

  

  According to HCV status, we found a stronger association between low TGF-β1 concentrations and the risk of death from HCC among the HCV-positive group compared to the HCV-negative group, suggesting that the predictive value of TGF-β1 is more potent in higher risk HCV-positive individuals. This findi

• Bindarit In conclusion the genetic diversity of

  2018-11-14

  

  In conclusion, the genetic Bindarit of P. jirovecii appears limited, suggesting a constant exchange between human individuals and the simultaneous presence of several genotypes in a given individual. On this constant exchange background, some temporal and geographical evolutions of genotypes were o

• Specifications table br Value of the data br

  2018-11-14

  

  Specifications table Value of the data Data, experimental design, materials and methods Using the 2D-DIGE approach we have obtained relevant information on the changes in abundance of most stavudine implicated in major canonical metabolic pathways [1]. Supplementary Table 1 lists all the iden

• br Data The data provided in this data article compliment

  2018-11-14

  

  Data The data provided in this data article compliment the original research article that described the transformation of two subcutaneous implantable cardioverter defibrillator vectors into an 8-lead surface ECG. Fig. 1 illustrate the location of the electrodes on the precordium used during data

• br Experimental design materials and methods br

  2018-11-14

  

  Experimental design, materials and methods Acknowledgments This work was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq 44371/2014-0), Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ E26/110.271/2014) and Programa Estratég

• br Material and methods br Results br

  2018-11-14

  

  Material and methods Results Discussion This study took a first step at evaluating the comparative neural responses during incentive anticipation among adolescents across the three most prevalent substances of abuse (alcohol, tobacco, and cannabis). We focused on the NAcc, an area within th

• br Conclusion In summary our study suggests that activation

  2018-11-14

  

  Conclusion In summary, our study suggests that activation in both the default network and fronto-parietal network during spatial working memory contributes to individual differences in behavioral performance even at a young age. In a group of youth 9–12 years of age, across participant difference

• NHS-LC-Biotin Supplier br Conclusions A greater demand on ex

  2018-11-14

  

  Conclusions A greater demand on executive control functions might entail greater difficulties controlling retaliatory responses to negative treatment in the heat of the moment of everyday interactions with peers. In turn, retaliatory responses are likely to provoke excluders, which could elicit n

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