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br In March the United
2019-04-29
In March, 2016, the United Nations Statistics Commission agreed upon the metrics used to measure progress towards, or away from, the new Sustainable Development Goals (SDGs). These so-called indicators define the real-world, measurable counterparts to the targets within the visionary goals of the
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br Conflict of interest br Author Contributions br Acknowled
2019-04-28
Conflict of interest Author Contributions Acknowledgments Case Report The general physical examination revealed an obese man with a heart rate of 140/minute but was otherwise unremarkable. The cardiac exam revealed an irregular rhythm. The abdominal exam revealed no tenderness or hepatos
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br The main challenges to ensuring optimal nutrition of chil
2019-04-28
The main challenges to ensuring optimal nutrition of children in low-income and middle-income settings are prevention of undernutrition—including intrauterine growth restriction, stunting, and micronutrient deficiencies—and avoidance of becoming overweight. Birth cohort studies show that linear gr
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Based on these preliminary clinical
2019-04-28
Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1
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br Introduction Once metastatic breast cancer cells are in
2019-04-28
Introduction Once metastatic breast cancer her2 inhibitor are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade th
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order CP-673451 For single shot techniques like the CBA
2019-04-28
For single-shot techniques, like the CBA, a modified spiral mapping catheter has been introduced for the identification of PVPs prior to ablation and also for monitoring purposes during the ablation process [6]. The Achieve™ Mapping Catheter (AC) is an intra-cardiac electrophysiological diagnostic c
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The review Bile acid receptor
2019-04-28
The review “Bile reverse transcriptase inhibitors receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides a
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La representaci n colectiva de
2019-04-28
La representación colectiva de los indígenas se caracteriza por el tono apologético, idealizado, en el que el uso abundante de los superlativos contribuye glycine transporter resaltar hiperbólicamente la naturaleza pacífica del nativo como “buen salvaje”: Siguiendo el esquema de las oposiciones bin
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Uma pena mas tudo n
2019-04-28
Uma pena, mas tudo não passou de uma estratégia de venda, uma reunião de escritores que ficou somente na mediação do editor. Estratégia, aliás cada vez mais usada desde buy ARQ 621 tão comentada entrada da literatura brasileira no mercado internacional motivada principalemente pela retomada dos proj
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br Conflict of interest br Acknowledgments
2019-04-26
Conflict of interest Acknowledgments This research was supported by the Grants from the National Natural Science Foundation of China (No. 31270820 and No. 81230061 to Wei-Dong Han, No. 81402567 to Ya-jing Zhang) and was partially supported by a Grant from the National Basic Science and Develop
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br Conclusion br Conflict of interest br Introduction
2019-04-26
Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu
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In a case similar to ours presented by
2019-04-26
In a case similar to ours, presented by Seres et al. [14] in which LVNC was associated with polymorphic VT, the value of QT interval was also difficult to ascertain because of the advanced LBBB. The onset of the polymorphic VT was similar to ours, but neither pause-dependence nor post-PVB lengthenin
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A recent analysis recommended axillary
2019-04-26
A recent analysis recommended axillary staging by sentinel lymph node biopsy, and administration of adjuvant radiotherapy and endocrine therapy after breast conserving surgery for mucinous carcinoma. Park et al. concluded that adjuvant chemotherapy could potentially be omitted in cases with favorab
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The effects of zoledronic acid are most
2019-04-26
The effects of zoledronic SCH527123 are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Where
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br Methods br Results br
2019-04-26
Methods Results Discussion One of the hallmarks of cancer is the ability of cancer ampk pathway to evade apoptosis. Inhibition of apoptosis not only enhances the survival of cancer cells but also facilitates their escape from chemotherapy [5]. Therefore, apoptosis regulatory mechanisms are
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